Collaborating, Learning, and Adapting (CLA) involves strategic collaboration, continuous learning, and adaptive management. CLA approaches to development include collaborating intentionally with stakeholders to share knowledge and reduce duplication of effort, learning systematically by drawing on evidence from a variety of sources and taking time to reflect on implementation, and applying learning by adapting intentionally. Strategic collaboration, continuous learning, and adaptive management connect all components of the Program Cycle. CLA can help USAID program in a way that is coordinated, grounded in evidence, and adjusted as necessary.