This is a handbook, it provides guidance for designing and implementing a monitoring and evaluation (M&E) system and it provides step-by-step guidance for operationalizing this commitment. Each topic includes its own set of standards, which emphasizes the key messages and quality considerations relevant to the topic. This handbook is for programming staff at all levels, including M&E staff, field staff, project managers and program officers. It highlights each role in multiple steps. The content of this handbook complements the information provided in ProPack I, ProPack II and ProPack III. Staff should have a solid foundation in ProPacks I, II and III in order to maximize the utility of this guidance. The guidance is intended to be dynamic and to engage staff members in the critical thinking required to design and implement an M&E system. It was published in 2008 and revised in 2012 by Catholic Relief Services CRS.