According to the World Health Organization (WHO), antimicrobial resistance (AMR) kills about 700,000 people worldwide annually, with the majority of those deaths occurring in developing countries. To address this health crisis, Jordan’s Ministry of Health (MOH) is implementing a National Action Plan (NAP) to combat AMR. A significant counterpart in this endeavor is the US Agency for International Development (USAID) Medicines, Technologies, and Pharmaceutical Services (MTaPS) Program, aligned with its Objective 4: Enhancing pharmaceutical services, product availability, and patient-centered care to achieve optimal health outcomes. MTaPS strategically crafted an Antimicrobial Stewardship Program (ASP) tailored for healthcare facilities, aiming to support both the MOH and the Royal Medical Services (RMS), pivotal healthcare providers in Jordan, in executing the AMR-focused NAP.